I love this comic SO much! Its just so believable and all the characters are really thought out well. I just thought I'd put my voice list for you guys. This is the what I hear in my head when ever someone speaks.
Alexial - Missy Peregrym
Brendan - Jay Baruchel
Steven - William Mosely
Brutus - Michael Cera
Nancy - Melissa McCarthy
Lyle - Mark Ruffalo
Alejandro - Valente Rodriguez
Sophia - Loretta Devine
Mary Anne - Leslie Mann
Regina - America Ferrera
Lucille - Darth Vader (just the breathing)
I politely left out Nii and Chuck because neither of them ever really speak. Lolz